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Evolutionary Genomics
December 29, 2025
Why Evolution Is the Missing Dimension in Variant Interpretation
Jill Pecon-Slattery
Why Population Databases Can’t Fix the VUS Crisis
Why Human-to-Human Comparisons Miss 99.8% of Evolutionary History
Why Variant Interpretation Still Takes Months: The Hidden Cost of Manual Filtering
The VUS Bottleneck Explained (And Why It Is Getting Worse Every Year)
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